http://www.bmj.com/content/345/bmj.e7293
How to diagnose diabetes. The standard way is to do a glucose tolerance test, with a fasting and 2hour blood test. Now it seems that doing a single test of longer term sugar, HbA1c, above 6.5% (48 mmol/mol) would be enough. Either way, diagnosis and treatment in diabetes is essential!
http://circ.ahajournals.org/content/126/20/2381.short
Efficacy and Safety of the Novel Oral Anticoagulants in Atrial Fibrillation: A Systematic Review and Meta-Analysis of the Literature-CIRCULATION 2012;126;20:Page2381
Novel oral anticoagulants (Dabigatran, Rivaroxaban, Apixaban, Edoxaban), have been proposed as alternatives to vitamin K antagonists (warfarin and Coumadin) for the prevention of stroke and systemic embolism in patients with atrial fibrillation. This systematic of randomized, controlled trials looked at 12 studies (3 administering Dabigatran, 4 administering Rivaroxaban, 2 administering Apixaban, and 3 administering Edoxaban) enrolling >50 000 patients. Novel oral anticoagulants significantly reduced death, and stroke or systemic embolism. Furthermore, these drugs showed a trend toward reduced major bleeding, with a significant reduction of intracranial (brain) haemorrhage. They need to be proven to be cost effective, but they appear to be an advance on current therapy.