Ezetimibe (Brand name: Ezetrol) is typically prescribed as an add-on treatment to statins when LDL cholesterol levels are not adequately reduced. It may also be recommended if you are unable to tolerate statins or if statin therapy alone is ineffective. Ezetimibe is available by prescription only and comes in tablet form.
It can also be combined with other medications:
- With simvastatin, a type of statin, it is marketed under the brand name Inegy.
- With bempedoic acid, it is known as Nustendi.
How does Ezetimibe Work?
Ezetimibe helps to lower cholesterol by reducing the amount absorbed from your diet. It generally lowers cholesterol levels within two weeks.
How do I take Ezetimibe?
You can take this medication with or without food.
What are the Side Effects of Ezetimibe?
Common side effects include abdominal pain and diarrhoea, affecting around 1 in 100 people.
Rare side effects may include:
- Muscle pain, tenderness, weakness, or cramps
- Yellowing of the whites of your eyes or your skin (less noticeable on brown or black skin), pale stools, and dark urine – potential signs of liver issues
- Severe stomach pain (under the ribs) – which may indicate pancreas problems
Who Should NOT take Ezetimibe?
You should not take Ezetimibe if you:
- have ever had an allergic reaction to ezetimibe or any other medication
- have liver problems
- are pregnant, planning to become pregnant, or breastfeeding
