These agents lower cholesterol by reducing its production in the liver. They are well tolerated and have a large amount of evidence showing that they reduce heart attacks and stroke. If your risk of death, heart attack or stroke is more that 2% annually, you should be on a statin. We can calculate your risk and advise on which agent and what dose you need to be on. Although you can get muscle aches, these tablets are remarkably well tolerated and save lives.
Statin |
Standard dose |
Maximum dose |
Maximum LDL reduction |
Pravastatin |
40 mg |
40 mg |
1.38 mmol/l |
Simvastatin |
40 mg |
40 mg |
2.01 mmol/l |
Atorvastatin |
40 mg |
80 mg |
2.58 mmol/l |
Rosuvastatin |
10 mg |
40 mg |
2.64 mmol/l |
Table of statins and possible cholesterol reductions.