Ticagrelor, is a new drug that is more powerful than Clopidogrel. It is used in in high risk cases, when clopidogrel alone may be inadequate or has been shown not to work. It has associated bleeding risk as it is a powerful agent. It is usually combined with aspirin, after stents, or you have had a heart attack. It is not used unless strongly indicated. Unlike Prasugrel or Aspirin, it has to be taken twice a day.